stats4PT
What can observations warrant?
Clinical inquiry
From what is known to who is here.
Instantiation is the work of bringing population evidence, mechanisms, and movement knowledge into a patient-specific model that can be questioned, revised, and acted upon without hiding uncertainty.
Population knowledge
This persongoals · findings · context · time
Instantiation
A clinical model is made specific, not merely retrieved.
Evidence describes groups, mechanisms describe possible processes, and models organize relationships. None of those is yet a conclusion about one person.
The clinician instantiates that knowledge by mapping it to the person’s observations, history, goals, environment, response over time, and plausible alternatives. The resulting model is provisional: useful enough to guide the next action, explicit enough to revise.
Population knowledgePatient-specific inquiry
Estimates average patterns and variationAsks which patterns plausibly apply here
Represents mechanisms across contextsTests mechanisms against individual findings
Constrains what should be believedRevises belief as the person responds
Supports but does not determine careIntegrates goals, values, feasibility, and judgment
Clinical Inquiry Ecosystem
Distinct kinds of knowledge, deliberately connected.
Sean Collins’s broader program separates discovery, mechanism, movement-domain scholarship, knowledge integration, and patient-specific inference so each can be inspected on its own terms.
Physiolog
How are effects generated?
Movement Systems
How is movement produced and changed?
Models4PT
How does the knowledge fit together?
Clinical Inference Engine
What may be true for this person?
This is a conceptual and scholarly flow, not an automated pipeline. Each project remains independently governed and versioned.
Safeguards
Clinical specificity without false certainty.
Population is not person
Group estimates constrain reasoning; they do not substitute for individual findings and context.
Observation is not explanation
A visible pattern may have multiple sufficient mechanisms, and the same mechanism may produce different patterns.
A model is not the patient
Models are explicit tools for inquiry. Their omissions, uncertainty, and revision history remain visible.
Movement gives clinical inquiry something indispensable: