Live acquisition
Local browser software displays ECG, five-beat heart rate, chest tilt, signal quality, protocol phase, symptoms, BP, and end-tidal CO₂ observations.
HMS Lab · Projects
Tilt ECG Measurement and Physiology Review.
An in-progress development project connecting synchronized Movesense ECG and chest-angle acquisition with governed, de-identified review of the physiologic response to orthostatic stress.
In progress
HMS-PROJ-007
Develop the complete measurement workflow before extending its use.
The current system records native ECG and inertial signals during head-up tilt, preserves them as checksum-verified artifacts, and supports a separate clinical physiology review without storing direct identifiers.
Representative teaching and clinical-development workflows are now being used to refine acquisition, event timing, angle calibration, analysis, review, and report export. This development status does not establish diagnostic validity, normative reference values, or readiness for distribution.
View the public implementationAcquisition to report
Keep every transformation visible and reviewable.
Raw physiological signals remain unchanged. Calibration, interval decisions, eligibility rules, reviewer conclusions, and report approval are recorded as derived provenance.
- 01Acquire
Stream ECG and chest orientation from a Movesense sensor during a governed tilt-table workflow.
- 02Preserve
Write native-rate signals, exact events, metadata, checksums, and a five-second summary.
- 03Verify
Confirm source integrity and review the relationship between sensor angle and achieved table angle.
- 04Analyze
Review beat-to-beat HR, R–R intervals, BP, end-tidal CO₂, symptoms, HRV, and Poincaré measures.
- 05Report
Approve an immutable review record and export a de-identified portrait report.
Current development
Working software, bounded evidence, open questions.
Engineering validation demonstrates that the components can operate together. It does not establish clinical interpretation or scientific validity.
Governed records
Native-rate ECG and IMU samples, events, metadata, summaries, and checksums are retained outside the public repository.
Physiology review
The review application derives beat-to-beat HR and R–R relationships, segmented HRV, Poincaré measures, and time-aligned clinical observations.
Reviewed report
Reviewer decisions and source checksums are preserved in a new immutable record before a de-identified portrait report can be exported.
Boundary
Development software does not replace the clinical system.
Approved ECG, blood-pressure, end-tidal CO₂, table-safety, supervision, stopping, and emergency procedures remain authoritative during clinical testing.
The applications do not request a name, medical record number, date of birth, or other direct identifier. Clinical recordings and reports remain governed even when direct identifiers are absent, and they are not website content.
After workflow refinement
Two distinct next questions.
Distribution and research each require their own evidence, governance, and decision process. Neither follows automatically from a successful development workflow.
Can other qualified users operate and support the system safely?
This requires a defined intended use, supported hardware and software, installation and recovery procedures, training, validation fixtures, documentation, support, and the applicable institutional and regulatory determinations.
Does individualized gravity load explain orthostatic responses better than angle?
A future prospective protocol may compare active orthostatic stress with passive head-up tilt in people without signs, symptoms, or a diagnosis of dysautonomia, while comparing corrected angle with measured gravity orientation and anthropometric vertical-column estimates. Standing height is a possible initial proxy, but direct heart-to-foot or heart-to-head distance may be more relevant. The sensor does not directly measure vascular pressure, and protocols, outcomes, consent, governance, and analysis must be defined before enrollment.